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DATE: 2025.09.26
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  • インバウンド・アウトバウンド医学研究部門
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Modeling of hepatitis B virus infection spread in primary human hepatocytes

Shi Z, Tsuge M, Collier N, Takeuchi Y, Uchida T, Rutter CM, Teraoka Y, Uprichard SL, Ishida Y, Tateno C, Ozik J, Dahari H, Chayama K.J Virol. 2025 Sep 23;99(9):e0092725. doi: 10.1128/jvi.00927-25. Epub 2025 Aug 4.

PMID: 40757857  Free PMC article.

DATE: 2025.07.18
  • 論文
  • ワンヘルス研究部門
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Generation of Recombinant Authentic Live Attenuated Human Rotavirus Vaccine Strain RIX4414 (Rotarix®) from Cloned cDNAs Using Reverse Genetics

Saori Fukuda, Masanori Kugita, Kanako Kumamoto, Yuki Akari, Yuki Higashimoto,
Shizuko Nagao, Takayuki Murata, Tetsushi Yoshikawa, Koki Taniguchi and Satoshi Komoto

MDPI – viruses
https://www.mdpi.com/1999-4915/16/8/1198

DATE: 2025.07.18
  • 論文
  • ゲノムワイド感染症研究部門
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Identification of genetic determinants of antibiotic resistance in Helicobacter pylori isolates in Vietnam by high-throughput sequencing

Phuc Hoang Bui , Trang Ngoc Minh Cao , Thanh Truc Tran , Takashi Matsumoto, Junko Akada & Yoshio Yamaoka

BMC Microbiology volume 25, Article number: 264 (2025)
https://doi.org/10.1186/s12866-025-03990-w

DATE: 2025.07.18
  • 論文
  • ゲノムワイド感染症研究部門
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Fine-scale population structure of Japanese Helicobacter pylori provides new anthropological and epidemiological insights

Kohei Tomonari, Batsaikhan Saruuljavkhlan, Ricky Indra Alfaray, Kartika Afrida Fauzia, Osamu Matsunari, Daisuke Chinda, Tadashi Shimoyama, Phawinee Subsomwong,

Nagisa Kinjo, Tetsu Kinjo, Yasuo Hanamure, Masato Shinzato, Rumiko Suzuki, Fukunori Kinjo, Shigeru Takigami, Toshio Fujioka, Takeshi Matsuhisa, Junko Akada,

Takashi Matsumoto and Yoshio Yamaoka

RESEARCH ARTICLE Tomonari et al., Microbial Genomics 2025;11:001419
https://doi.org/10.1099/mgen.0.001419

DATE: 2025.07.18
  • 論文
  • 共同研究成果

Targeted labeling and depletion of alveolar macrophages using VeDTR mouse technology

Yuki Nakayama, Miwa Sasai, Ayumi Kuratani, Masaaki Okamoto, Daisuke Okuzaki, Kentaro Yamamoto, Chikako Ono, Masaya Yamaguchi,
Shigetada Kawabata, Noriko Shinjyo, Yasutaka Okabe, Yoshiharu Matsuura, Manabu Ato, Masahiro Yamamoto

iScience 28, 111975, March 21, 2025
https://doi.org/10.1016/j.isci.2025.111975

DATE: 2025.07.18
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Hybrid sequence-based analysis reveals the distribution of bacterial species and genes in the oral microbiome at a high resolution

Masaya Yamaguchi, Toshihiro Uchihashi, Shigetada Kawabata

Biochemistry and Biophysics Reports Volume 38, July 2024, 101717
https://doi.org/10.1016/j.bbrep.2024.101717

DATE: 2025.07.18
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Identifying Genetic Variations in emm89 Streptococcus pyogenes Linked to Severe Invasive Infections

Masayuki Ono, Masaya Yamaguchi , Daisuke Motooka, Yujiro Hirose, Kotaro Higashi,Tomoko Sumitomo, Tohru Miyoshi-Akiyama, Rumi Okuno, Takahiro Yamaguchi,

Ryuji Kawahara, Hitoshi Otsuka, Noriko Nakanishi, Yu Kazawa, Chikara Nakagawa, Ryo Yamaguchi, Hiroo Sakai, Yuko Matsumoto, Tadayoshi Ikebe, Shigetada Kawabata

Microbiology and Infectious Disease
https://doi.org/10.7554/eLife.101938.2

DATE: 2025.07.18
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A comprehensive analysis of antimicrobial resistance of clinical emm89 Streptococcus pyogenes in Japan

Weichen Gong, Masayuki Ono, Masaya Yamaguchi, Daisuke Motooka, Yujiro Hirose, Kotaro Higashi, Momoko Kobayashi, Eri Ikeda, Tomoko Sumitomo, Rumi Okuno,

Takahiro Yamaguchi, Ryuji Kawahara, Hitoshi Otsuka, Noriko Nakanishi, Yu Kazawa, Chikara Nakagawa, Ryo Yamaguchi, Hiroo Sakai, Yuko Matsumoto,

Tadayoshi Ikebe and Shigetada Kawabata

JAC Antimicrob Resist
https://doi.org/10.1093/jacamr/dlaf017

DATE: 2025.07.18
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Far-East Asian Toxoplasma isolates share ancestry with North and South/Central American recombinant lineages

Fumiaki Ihara, Hisako Kyan, Yasuhiro Takashima, Fumiko Ono, Kei Hayashi, Tomohide Matsuo, Makoto Igarashi, Yoshifumi Nishikawa, Kenji Hikosaka, Hirokazu Sakamoto, Shota Nakamura,

Daisuke Motooka, Kiyoshi Yamauchi, Madoka Ichikawa-Seki, Shinya Fukumoto, Motoki Sasaki, Hiromi Ikadai, Kodai Kusakisako, Yuma Ohari, Ayako Yoshida, Miwa Sasai,

Michael E. Grigg & Masahiro Yamamoto

Nature Communications volume 15, Article number: 4278 (2024)
https://doi.org/10.1038/s41467-024-47625-6

DATE: 2025.07.18
  • 論文
  • 感染症病態研究部門
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CCR2-dependent placental migration of inflammatory monocytes suppresses abnormal pregnancies caused by Toxoplasma gondii infection

Naganori Kamiyama, Mai Ueno, Yuma Sasaki, Thanyakorn Chalalai, Nozomi Sachi, Sotaro Ozaka, Yasuhiro Soga,

Yomei Kagoshima, Supanuch Ekronarongchai, Masaaki Okamoto, Masahiro Yamamoto and Takashi Kobayashi

International Immunology Vol. 37, No. 1, pp. 39–51
https://doi.org/10.1093/intimm/dxae046